What is Spravato?
Spravato (esketamine) is an FDA-approved nasal spray used for treatment-resistant depression (TRD) and certain mood disorders. Unlike traditional antidepressants, it acts rapidly by targeting specific brain receptors, providing relief for individuals who have not responded to conventional treatments. Spravato is administered under medical supervision and is often combined with oral antidepressants for enhanced effectiveness. Many insurance plans cover Spravato, making it a more accessible option for those in need of advanced depression treatment.


How Does Spravato Work?
Spravato works by targeting NMDA receptors in the brain, helping to form new neural connections and support mood regulation. Its distinct mechanism provides rapid relief, often within hours, making it a valuable option for those in need of urgent intervention. The treatment is administered in a controlled medical setting, where patients are carefully monitored by healthcare professionals to ensure safety and effectiveness.
Conditions We Treat
Experience the Change and Growth You Deserve

Depression
With a 70% greater efficacy compared to SSRIs, research highlights ketamine as one of the most significant breakthroughs in mental health treatment in decades.

Suicidal Ideation
Suicidal ideation, often stemming from depression or other underlying conditions, can be effectively treated with ketamine infusions.

Bipolar Disorder
Characterized by extreme mood swings, including mania and depression. Spravato® helps manage bipolar depression when other treatments fail.

PTSD (Post-Traumatic Stress Disorder)
A condition triggered by trauma, leading to flashbacks and anxiety. Spravato® helps reduce PTSD symptoms and restore emotional balance.

Anxiety Disorders
Severe anxiety can disrupt daily life. Spravato® may help those who don’t respond to traditional treatments.

Alcohol Addiction
Alcohol dependence affects mental and physical health. Spravato® may help reduce cravings and support recovery.

OCD (Obsessive-Compulsive Disorder)
Intrusive thoughts and repetitive behaviors can be debilitating. Spravato® is being explored as an alternative treatment for severe OCD.
FAQ
Popular Questions
Take a look at some science-backed answers to common questions about Spravato.
Spravato (esketamine) is an FDA-approved nasal spray derived from ketamine. It works by targeting NMDA receptors in the brain, rapidly alleviating symptoms of treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts.
Spravato is typically prescribed for adults with treatment-resistant depression (TRD) or those experiencing major depressive disorder (MDD) with suicidal ideation. Patients must be under the supervision of a healthcare provider in a certified treatment center.
Spravato is a nasal spray self-administered under medical supervision in a clinical setting. After taking the dose, patients remain under observation for at least two hours to monitor for side effects.
Many patients experience symptom relief within hours or days after starting treatment, making it significantly faster-acting than traditional antidepressants.
Common side effects include dizziness, dissociation, nausea, drowsiness, and increased blood pressure. Due to these effects, patients are advised not to drive or operate heavy machinery until the following day.
Treatment schedules vary, but initial therapy typically involves twice-weekly sessions for the first month, followed by a gradual reduction in frequency based on patient response and provider recommendations.